Obesity affects graft function but not graft loss in kidney transplant recipients

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Long-term graft function changes in kidney transplant recipients

Background. Monitoring changes in glomerular filtration rate (GFR) is the recommended method for assessing the progression of kidney disease. The aim of this study was to assess the decline of graft function defined by the annualized change in GFR and the factors which affect it.Methods. Four thousand four hundred and eighty-eight patients, transplanted during the years 1990, 1994, 1998 and 200...

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Associations of pre-transplant anemia management with post-transplant delayed graft function in kidney transplant recipients.

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Derivation of a Predictive Model for Graft Loss Following Acute Kidney Injury in Kidney Transplant Recipients

BACKGROUND Acute kidney injury (AKI) is common in the kidney transplant population. OBJECTIVE To derive a multivariable survival model that predicts time to graft loss following AKI. DESIGN Retrospective cohort study using health care administrative and laboratory databases. SETTING Southwestern Ontario (1999-2013) and Ottawa, Ontario, Canada (1996-2013). PATIENTS We included first-time...

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Association of pre-transplant statin use with delayed graft function in kidney transplant recipients

BACKGROUND Administration of HMG-CoA reductase inhibitors (statins), prior to ischemia or prior to reperfusion has been shown to decrease ischemia-reperfusion renal injury in animal studies. It is unknown whether this protective effect is applicable to renal transplantation in humans. The aim of this study was to determine the relationship between prior statin use in renal transplant recipients...

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Significant racial differences in the key factors associated with early graft loss in kidney transplant recipients.

BACKGROUND There is continued and significant debate regarding the salient etiologies associated with graft loss and racial disparities in kidney transplant recipients. METHODS This was a longitudinal cohort study of all adult kidney transplant recipients, comparing patients with early graft loss (<5 years) to those with graft longevity (surviving graft with at least 5 years of follow-up) acr...

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ژورنال

عنوان ژورنال: Journal of International Medical Research

سال: 2020

ISSN: 0300-0605,1473-2300

DOI: 10.1177/0300060519895139